Coronavirus COVID-19 Weekly Update 30th November 2020

Coronavirus COVID-19 Weekly Update 30th November 2020

Weekly update published on MedShr: 30th November 2020
Last updated: 30th November 2020

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Coronavirus COVID-19 Weekly Update 30th November 2020

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of doctors to help improve patient care. Include #COVID19 in your case title.

Please email COVID@medshr.net if you have any data, publications or information you would like to share.


Global Impact of COVID-19 to Date

WHO official data, reported on 29th Nov 2020

COVID-19 Cumulative Global Cases

WHO official data, reported on 29th Nov 2020

Total UK COVID-19 Cases

As of 30th Nov 09:00 (GMT) - Data for 24 hour period, reported on 29-11-20

Total UK daily cases over past month

COVID-19 in the African Region

As of 30th Nov 09:00 (GMT) - Data for 24 hour period, reported on 29-11-20

COVID-19 in the Eastern Mediterranean Region

As of 30th Nov 09:00 (GMT) - Data for 24 hour period, reported on 29-11-20

Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from scientific journals:


Editorials, Research Articles and Commentary:

NEJM: A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia

Simonovich VA, Burgos Pratx LD, Scibona P, et al. A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia. N Engl J Med. 2020 Nov 24. doi: 10.1056/NEJMoa2031304. Epub ahead of print. PMID: 33232588.

Cell: Functional SARS-CoV-2-specific immune memory persists after mild COVID-19

Rodda LB, Netland J, Shehata L, et al. Functional SARS-CoV-2-specific immune memory persists after mild COVID-19. Cell. 2020 Nov 23. ISSN 0092-8674. DOI: 10.1016/j.cell.2020.11.029

Thorax: 'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19

Mandal S, Barnett J, Brill SE, et al. 'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. Thorax. 2020 Nov 10:thoraxjnl-2020-215818. doi: 10.1136/thoraxjnl-2020-215818. Epub ahead of print. PMID: 33172844; PMCID: PMC7661378.

Brain Communications: Frequent neurocognitive deficits after recovery from mild COVID-19

Woo MS, Malsy J, Pöttgen J. Frequent neurocognitive deficits after recovery from mild COVID-19. Brain Communications. 2020 Nov 23; fcaa205. DOI: 10.1093/braincomms/fcaa205

PLOS One: The impact of believing you have had COVID-19 on self-reported behaviour: Cross-sectional survey

Smith LE, Mottershaw AL, Egan M, Waller J, Marteau TM, Rubin GJ. The impact of believing you have had COVID-19 on self-reported behaviour: Cross-sectional survey. PLoS One. 2020 Nov 4;15(11):e0240399. doi: 10.1371/journal.pone.0240399. PMID: 33147219; PMCID: PMC7641362.

JAMA Intern Med. Effect and Reach of Medical Articles Posted on Preprint Servers During the COVID-19 Pandemic (research letter)

Jung YEG, Sun Y, Schluger NW. Effect and Reach of Medical Articles Posted on Preprint Servers During the COVID-19 Pandemic. JAMA Intern Med. 2020 Nov 9:e206629. doi: 10.1001/jamainternmed.2020.6629. Epub ahead of print. PMID: 33165545; PMCID: PMC7653533.


Latest Developments in the News:

WHO Weekly Situational Reports: Epidemiological and Operational


Africa

WHO: African Health Ministers urge greater vigilance in COVID-19 fight 

WHO: WHO urges African countries to ramp up readiness for COVID-19 vaccination drive

BBC: Coronavirus in Africa: What you need to know about the Covid-19 vaccines

BBC: Coronavirus in Africa tracker

WHO in the African Region: COVID-19


Eastern Mediterranean

The Lancet: Afghanistan braced for second wave of COVID-19 

WHO: Lebanon - WHO supports civil/military cooperation on COVID-19 database

WHO: Regional COVID-19 response: success stories

WHO in the Eastern Mediterranean Region: COVID-19


United Kingdom

BMJ: Partha Kar: Delivering covid vaccine—a team effort (Views and Reviews)

BBC: Covid: Risk of third wave 'if we don't get balance right' - Raab

RCN: RCN reveals expectations for COVID-19 vaccine rollout

BBC: Oxford/AstraZeneca Covid vaccine 'dose error' explained

BBC: Lockdown rules: What Covid tier is your area in and what are the restrictions?

UK Government Advice

Coronavirus (COVID-19) in the UK


Global Health

Nature: Why Oxford's positive COVID vaccine results are puzzling scientists 

BMJ: Will covid-19 vaccines be cost effective—and does it matter?

Nature: Why emergency COVID-vaccine approvals pose a dilemma for scientists

Nature: The COVID vaccine challenges that lie ahead

The Lancet: Maintaining the HIV response in a world shaped by COVID-19

UNICEF: 320,000 children and adolescents newly infected with HIV in 2019, 1 every 100 seconds

BMJ: Remdesivir: a pendulum in a pandemic

BMJ: The curious case of the Danish mask study

Nature: How Iceland hammered COVID with science

NEJM Journal Watch: Prior Coronavirus Infection May Affect COVID-19 Severity


Useful Sources for Latest Developments and News

WHO: Coronavirus disease (COVID-19) pandemic (including links to regional offices)

United Nations: COVID-19 Response

Johns Hopkins University & Medicine: Coronavirus Resource Center

Centers for Disease Control and Prevention

European Centre for Disease Prevention and Control

Médecins Sans Frontières: Response and News Articles

BBC: Covid-19 pandemic: Tracking the global coronavirus outbreak

Financial Times: Coronavirus tracker: the latest figures as countries fight Covid-19 resurgence

Harvard Medical School: Coronavirus Resource Center

Our World in Data: Coronavirus Pandemic (COVID-19) - Statistics and Research


Educational Resources:


WHO: COVID-19 Course Series

"Real-time training during global emergencies is critical for effective preparedness and response. The COVID-19 channel provides learning resources for health professionals, decision-makers and the public for the outbreak of coronavirus disease (COVID-19)." (WHO 2020)


MedShr Open: COVID-19 Weekly Article - Long COVID

Last week's COVID-19 Open Article focuses on post-COVID-19 syndrome, widely known as Long COVID. The article highlights the origins of the term, explores what is currently known about epidemiology and risk factors, and considers the research challenges moving forward. Current and future management approaches are also considered, including the potential challenges of caring for patients with Long COVID in low- and middle-income countries.


Public Health Emergency COVID-19 Initiative - PubMed Central

An open collection of COVID-19 and coronavirus-related publications, and the available data supporting them, from over 50 publishers to support the ongoing public health emergency response efforts (PMC).

Other Useful Resources:

Intensive Care Society (UK) Covid-19 Resource Hub

The Mid Yorkshire Hospitals NHS Trust COVID-19 Bulletins - A weekly bulletin detailing the "latest guidelines, research and reports relating to COVID-19"

NHS England: Coronavirus guidance for clinicians and NHS managers

CDC: COVID-19 Science Updates


Weekly Update by Dr Ryan Broll, MedShr Open Editorial Team, Medical Education Fellow

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