Coronavirus COVID-19 Daily Update 8th April 2020
Coronavirus COVID-19 Daily Update 8th April 2020
This update will be published daily at 12pm GMT and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.
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Global Impact of COVID-19 to Date
As of 8th April 09:00 (GMT)
COVID-19 Cumulative Global Cases
As of 8th April 09:00 (GMT)
Source: World Health Organisation
COVID-19 Global Active Cases Map
As of 8th April 09:00 GMT
Total UK COVID-19 Cases
As of 7th April
NB: Public Health England has now moved to a different reporting time for UK COVID-19 fatalities, as family consent is now needed to release mortality statistics. Hence the reported figures may not actually be the deaths that have taken place over the past 24 hours, meaning caution needs to be exercised when comparing figures from one day to the next.
Source: Public Health England
COVID-19 Cumulative UK Cases
As of 7th April
Source: Public Health England
COVID-19 Daily UK Cases
As of 7th April
Source: Public Health England
Coronavirus Infection trajectories
As of 8th April 2020
Source: informationisbeautiful
Source: informationisbeautiful
COVID-19 Key Data
Source: informationisbeautiful
Source: informationisbeautiful
Source: J P Morgan
Source: J P Morgan
Excerpt from J P Morgan: Vaccine and anti-viral update; the Chloroquine controversy; Convalescent plasma (Last update 4th April 2020)
Critique of Study by Gautret el al, March 2020: Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial
non-randomized trial with only 36 patients, and had no discussion of outcomes
excluded 6 recipients that were not discussed, some of whom of required ventilation and/or died
started out with higher viral loads in the control group than in the infected patients, which could explain why the control group showed higher infected rates at the conclusion of the study
imputed more than 1/3 of the control group virus tests rather than measuring them
sourced its treatment group (unlike the control group) from a single medical center
Source: J P Morgan
Latest Developments
Africa
Coronavirus in 52 African countries, 10,000+ cases, 487 deaths, 993 recoveries
World Bank Surges Support to Address Coronavirus Outbreak in the Middle East and North Africa
Amref COVID-19 Africa Information Centre
WHO Africa Dashboard: Coronavirus (COVID-19)
Asia
Coronavirus: China reports no new deaths for first time since pandemic began
China has shut all of its wild animal markets – it was long overdue
Middle East
Coronavirus in the Middle East: everything you need to know about Covid-19
As covid-19 spreads, Arab states are clamping down
COVID-19: Turkey university begins passive immunisation
USA
Coronavirus: US records highest death toll in single day
Centers for Disease Control and Prevention website
US Coronavirus (COVID-19) website
United Kingdom
Coronavirus: Warning over daily death figures
3D Printing Community Responds to COVID-19 and Coronavirus Resources
UK Government Advice
Europe
Coronavirus: Paris bans daytime outdoor exercise
Coronavirus: Doctors at Spain's largest hospital 'winning COVID-battle little by little'
UK must learn from German response to Covid-19, says Whitty
Latest COVID-19 Publications
Some key recent publications to be aware of:
Covid-19: Why Germany’s case fatality rate seems so low
Published 7th April 2020
BMJ
Germany's low covid-19 fatality rate can be attributed partly to the nation’s early and high level of testing among a wide sample of the German population. While other countries were conducting a limited number of tests of older patients with severe cases of the virus, Germany was conducting many more tests that included milder cases in younger people.
Diagnostic Value and Dynamic Variance of Serum Antibody in Coronavirus Disease 2019
Published 3rd April 2020 (online ahead of print)
International Journal of Infectious Diseases
Investigation on the diagnostic value of serological test and dynamic variance of serum antibody in COVID-19. Concluded that a viral serological test is an effective diagnostic means for SARS-CoV-2 infection. The positive rate and titer variance of IgG are higher than that of IgM in COVID-19.
Caution and clarity required in the use of chloroquine for COVID-19
Published 2nd April 2020
The Lancet Rheumatology
Caution for use of chloroquine in the clinical setting, although shown to inhibit severe acute respiratory syndrome coronavirus 2 in vitro, benefit of clinical use is still under evaluation. Also care should be taken to review dosing regimens as it can accumulate in the body and reach a lethal dose.
Daily Update by Samantha Goh, MedShr Open Editorial Team, Medical Education Teaching Fellow
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