Coronavirus COVID-19 Weekly Update 26th July 2021

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Coronavirus COVID-19 Weekly Update 26th July 2021

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any anonymous educational COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of healthcare professionals to help improve patient care.

Please email COVID@medshr.net if you have any data, publications or information you would like to share.


Global Impact of COVID-19 to Date

Data from WHO Coronavirus Disease (COVID-19) Dashboard, reported on 26th July 2021

COVID-19 Cumulative Global Cases

Data from WHO Coronavirus Disease (COVID-19) Dashboard, reported on 26th July 2021

Global Vaccinations Against COVID-19

Official data collated by Our World in Data - data up to 25th July 2021

Source: Our World in Data

For full vaccination data, Our World in Data state: "Total number of people who received all doses prescribed by the vaccination protocol. This data is only available for countries which report the breakdown of doses administered by first and second doses."

Mathieu, E., Ritchie, H., Ortiz-Ospina, E. et al. A global database of COVID-19 vaccinations. Nat Hum Behav (2021)


Total UK COVID-19 Cases

Data for 24 hour period, reported on 25-07-21

UK total daily cases over past month

COVID-19 in the African Region

Data for 24 hour period, reported on 25-07-21

COVID-19 in the Eastern Mediterranean Region

Data for 24 hour period, reported on 25-07-21

Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from scientific journals


Nature Medicine: COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

Solís Arce JS, Warren SS, Meriggi NF, et al. COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries. Nat Med. 2021 Jul 16. doi: 10.1038/s41591-021-01454-y. Epub ahead of print. PMID: 34272499.

The Lancet Global Health: Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study

Jassat W, Mudara C, Ozougwu L, et al. Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study. Lancet Glob Health. 2021 Jul 9:S2214-109X(21)00289-8. doi: 10.1016/S2214-109X(21)00289-8. PMID: 34252381; PMCID: PMC8270522.

JAMA: Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial

Oldenburg CE, Pinsky BA, Brogdon J, et al. Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial. JAMA. 2021 Jul 16. doi: 10.1001/jama.2021.11517. Epub ahead of print. PMID: 34269813.

Nature Medicine: Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination 

Barros-Martins J, Hammerschmidt SI, Cossmann A, et al. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nat Med. 2021 Jul 14. doi: 10.1038/s41591-021-01449-9. Epub ahead of print. PMID: 34262158.

The Lancet: Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey

Tanriover MD, Doğanay HL, Akova M, et al. Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey. Lancet. 2021 Jul 17;398(10296):213-222. doi: 10.1016/S0140-6736(21)01429-X. Epub 2021 Jul 8. PMID: 34246358; PMCID: PMC8266301.

Scientific Reports: Placental response to maternal SARS-CoV-2 infection

Mourad M, Jacob T, Sadovsky E, et al. Placental response to maternal SARS-CoV-2 infection. Sci Rep. 2021 Jul 13;11(1):14390. doi: 10.1038/s41598-021-93931-0. PMID: 34257394; PMCID: PMC8277865.

Postgraduate Medical Journal: Healthcare workers’ (HCWs) attitudes and related factors towards COVID-19 vaccination: a rapid systematic review

Li M, Luo Y, Watson R, et al. Healthcare workers' (HCWs) attitudes and related factors towards COVID-19 vaccination: a rapid systematic review. Postgrad Med J. 2021 Jun 30:postgradmedj-2021-140195. doi: 10.1136/postgradmedj-2021-140195. Epub ahead of print. PMID: 34193545.

The Lancet Psychiatry: Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis 

Vai B, Mazza MG, Delli Colli C, et al. Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis. Lancet Psychiatry. 2021 Jul 15:S2215-0366(21)00232-7. doi: 10.1016/S2215-0366(21)00232-7. Epub ahead of print. PMID: 34274033.

BMJ: Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform

Williamson EJ, McDonald HI, Bhaskaran K, et al. Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform. BMJ. 2021 Jul 14;374:n1592. doi: 10.1136/bmj.n1592. PMID: 34261639; PMCID: PMC8278652.


Educational Resources:


WHO: COVID-19 Course Series and Vaccine Series

Johns Hopkins University: Understanding the COVID-19 Pandemic

BMJ Best Practice: Coronavirus disease 2019 (COVID-19) clinical decision support tool

BSAC and JAC-Antimicrobial Resistance: COVID-19 Resource Hub

Elsevier: COVID-19 Health Education resource center, including the Health Education Faculty Hub

NEJM: Covid-19 Vaccine Resource Center

BMJ: Covid-19 vaccination hesitancy 

BMJ: A living WHO guideline on drugs to prevent covid-19

NEJM: Covid-19 Rx: Treatment Simulations

BMJ: Interpreting a lateral flow SARS-CoV-2 antigen test

Nature Podcast: Coronapod: the latest on COVID and sporting events (24th July 2021)


MedShr Open: COVID-19 Articles and Learning Modules

The COVID-19 Hub on MedShr Open includes a selection of articles covering a range of topics related to COVID-19, ranging from emerging therapies, long-term effects of COVID-19, and considering the effects of the pandemic on other essential healthcare services. There are also new, free COVID-19 Learning Modules live in the the COVID-19 discussion group:


Global Health Data for COVID-19

Global.health - a Data Science Initiative - open public health COVID-19 dataset to advance the response to infectious diseases

The Institute for Health Metrics and Evaluation (IHME)


Research related to COVID-19

Below is a list of links to organisations who are making great efforts to categorise, evaluate and summarise the vast catalogue of COVID-19 research. If you discover any other great resources please feel free to share these in the comments section below.

Global research on coronavirus disease (COVID-19) - WHO Global research database and links to further research catalogues

LitCovid - a curated literature hub for tracking up-to-date scientific information about COVID-19

Public Health Emergency COVID-19 Initiative - PubMed Central

COVID-19 Science Updates - Centers for Disease Control and Prevention

Coronavirus Disease 2019 (COVID-19) Treatment Guidelines - National Institutes of Health

ClinicalTrials.gov - COVID-19 clinical trials

Finding the evidence: Coronavirus – Knowledge & Library Services - Public Health England

Coronavirus (COVID-19) - Cochrane resources and news - Cochrane


India and Pakistan COVID-19 Support Groups

New groups have been launched as part of MedShr's COVID-19 education programme in response to the current challenges in India and Pakistan. The groups are intended to be a dedicated place for all healthcare professionals to share information and resources, and discuss how to manage increasingly unwell patients with limited resources, as well as giving access to international experts in COVID-19.


Weekly Update by MedShr Open Editorial Team

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