Coronavirus COVID-19 Daily Update 21st March 2020

This update will be published daily at 12pm GMT and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of doctors to help improve patient care. Include #COVID19 in your case title.

Please email COVID@medshr.net if you have any data, publications or information you would like to share.

Global Impact of COVID-19 to Date

As of 21st March 09:00 (GMT)

Source: Johns Hopkins University & Medicine

COVID-19 Cumulative Global Cases

As of 20th March 09:00 (GMT)

Source: World Health Organisation

COVID-19 Global Active Cases Map

As of 21st March 09:00 GMT

Source: Johns Hopkins University & Medicine

Total UK COVID-19 Cases

As of 20th March 09:00 (GMT)

Source: Public Health England

COVID-19 Cumulative UK Cases

As of 20th March 09:00 (GMT)

Source: Public Health England

COVID-19 Daily UK Cases

As of 20th March 09:00 (GMT)

Source: Public Health England

Latest Developments

Italy

COVID-19 deaths pass 4000 as Italy records its highest single-day death toll

Italy Ministry of Health Website

China

For the 3rd day in a row, no new confirmed or suspected cases have been reported in Wuhan and in Hubei

Chinese Website of the Commission for Health

USA

New York, Illinois and Connecticut told residents to stay home except for essential activities, as US-Mexico border closed to non-essential travel

Centers for Disease Control and Prevention website

US Coronavirus (COVID-19) website

Official Coronavirus (COVID-19) in California website

United Kingdom

Boris Johnson announces closure of all UK pubs and restaurants

UK Government Advice

Reproduction and Fatality for Selected Human Viruses

This graph provides a comparison of the reproduction number and case-fatality ratio of COVID-19 against other viruses.

Source: McKinsey & Company

COVID-19 Case Fatality Rate by Age

The elderly are at a greatly increased risk of mortality.

Source: McKinsey & Company

Disease Phases Around the World

As of 16th March 09:00 (GMT)

Source: McKinsey & Company

COVID-19 Transmission Complexes

As of 16th March 09:00 (GMT)

Source: McKinsey & Company

Latest COVID-19 Publications

Some key recent publications to be aware of:

The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020

Published 17th February 2020

This study from the Chinese CDC includes over 72,000 COVID-19 cases and provides valuable epidemiological information around case fatality rate in different age groups, co-morbidities and gender. It also shows that case fatality rate among critical cases is almost 50%, and showed that, of the 1,716 COVID-19 cases in health workers, 14.8% were severe or critical.

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

Published 24th February 2020

This paper in JAMA provides an excellent concise summary of the key results from the above study from the Chinese CDC.

Author: Dr Daniel Livingstone, MedShr - Health Education England Fellow