Coronavirus COVID-19 Weekly Update 11th January 2021

Coronavirus COVID-19 Weekly Update 11th January 2021

Weekly update published on MedShr: 11th January 2021
Last updated: 11th January 2021

Every effort has been made to ensure that the information contained in this article is accurate and current at time of publication, but if you notice an error please contact covid@medshr.net and we will aim to address this. Please find MedShr’s full terms of service here.


Coronavirus COVID-19 Weekly Update 11th January 2021

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any anonymous educational COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of doctors to help improve patient care. Include #COVID19 in your case title.

Please email COVID@medshr.net if you have any data, publications or information you would like to share.


Global Impact of COVID-19 to Date

Data from WHO Coronavirus Disease (COVID-19) Dashboard, reported on 10th Jan 2021

Sources: World Health Organization, Johns Hopkins University & Medicine

Data related to 'patients recovered' and 'countries affected' based on data from Johns Hopkins University & Medicine, other data obtained from WHO Coronavirus Disease (COVID-19) Dashboard


COVID-19 Cumulative Global Cases

Data from WHO Coronavirus Disease (COVID-19) Dashboard, reported on 10th Jan 2021

Total UK COVID-19 Cases

As of 11th Jan 09:00 (GMT) - Data for 24 hour period, reported on 10-01-21

UK total daily cases over past month

COVID-19 in the African Region

As of 11th Jan 09:00 (GMT) - Data for 24 hour period, reported on 10-01-21

COVID-19 in the Eastern Mediterranean Region

As of 11th Jan 09:00 (GMT) - Data for 24 hour period, reported on 10-01-21

Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from scientific journals


Editorials, Research Articles and Commentary:

Nature Communications: Optimal COVID-19 quarantine and testing strategies 

Wells CR, Townsend JP, Pandey A, et al. Optimal COVID-19 quarantine and testing strategies. Nat Commun. 2021 Jan 7;12(1):356. doi: 10.1038/s41467-020-20742-8. PMID: 33414470; PMCID: PMC7788536.

NEJM: Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults 

Libster R, Pérez Marc G, Wappner D, et al. Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults. N Engl J Med. 2021 Jan 6. doi: 10.1056/NEJMoa2033700. Epub ahead of print. PMID: 33406353.

Science: The puzzle of the COVID-19 pandemic in Africa (Perspective)

Maeda JM, Nkengasong JN. The puzzle of the COVID-19 pandemic in Africa. Science. 2021 Jan 1;371(6524):27-28. doi: 10.1126/science.abf8832. PMID: 33384364.

NEJM: Maintaining Safety with SARS-CoV-2 Vaccines (Review)

Castells MC, Phillips EJ. Maintaining Safety with SARS-CoV-2 Vaccines. N Engl J Med. 2020 Dec 30. doi: 10.1056/NEJMra2035343. Epub ahead of print. PMID: 33378605.

medRxiv (Preprint, not peer reviewed): Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report

The REMAP-CAP Investigators, Gordon AC. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 - Preliminary report. medRxiv [preprint]. 2021 Jan 7. 21249390; doi: https://doi.org/10.1101/2021.01.07.21249390

The Lancet: 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

Huang C, Huang L, Wang Y, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. The Lancet. ePub ahead of print. 2021 Jan 8. DOI: 10.1016/S0140-6736(20)32656-8

Science: Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection 

Dan JM, Mateus J, Kato Y, et al. Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science. 2021 Jan 6:eabf4063. doi: 10.1126/science.abf4063. Epub ahead of print. PMID: 33408181.

JAMA Network Open: SARS-CoV-2 Transmission From People Without COVID-19 Symptoms 

Johansson MA, Quandelacy TM, Kada S, et al. SARS-CoV-2 Transmission From People Without COVID-19 Symptoms. JAMA Netw Open. 2021 Jan 4;4(1):e2035057. doi: 10.1001/jamanetworkopen.2020.35057. PMID: 33410879.

BMJ Global Health: What are SARS-CoV-2 genomes from the WHO Africa region member states telling us? (Commentary)

Lu L, Lycett S, Ashworth J, et al. What are SARS-CoV-2 genomes from the WHO Africa region member states telling us? BMJ Glob Health. 2021 Jan;6(1):e004408. doi: 10.1136/bmjgh-2020-004408. PMID: 33419930.


Latest Developments in the News:

WHO Weekly Situational Reports: Epidemiological and Operational


Africa

BBC News: South Africa coronavirus variant: What is the risk?

WHO: Strengthening Infection Prevention and Control across primary health care in the island of Rodrigues

Africa CDC: IPC reflections on COVID-19

BBC News: The Burundian refugee soap maker who is fighting coronavirus in Kenya

BBC: Coronavirus in Africa tracker

WHO in the African Region: COVID-19


Eastern Mediterranean

WHO: Five million COVID-19 cases reported in WHO's Eastern Mediterranean Region

WHO: Islamic Republic of Iran tackles COVID-19 by enhancing primary health care

MSF: Lebanon -  Overlapping crises increase needs and worsen access to care

WHO: Regional COVID-19 response: success stories

WHO in the Eastern Mediterranean Region: COVID-19


United Kingdom

BMJ: Covid-19 vaccination: What’s the evidence for extending the dosing interval? 

BBC News: Covid vaccine: How will the UK jab millions of people?

BMJ: Covid-19 has amplified moral distress in medicine 

BMJ: Covid-19: GPs can limit routine work to focus on vaccination, says NHS England

BBC: Lockdown rules: What Covid tier is your area in and what are the restrictions?

UK Government Advice

Coronavirus (COVID-19) in the UK


Global Health

Nature: Could new COVID variants undermine vaccines? Labs scramble to find out

Nature: Search for better COVID vaccines confounded by existing rollouts 

BMJ: Covax must go beyond proportional allocation of covid vaccines to ensure fair and equitable access 

BMJ: Covid-19: Arthritis drugs improve survival in intensive care patients, shows study 

LSHTM: Expert comment - Two potentially life-saving drugs for critically ill COVID-19 patients

WHO: Who can take the Pfizer-BioNTech COVID-19 vaccine?

WHO: WHO issues its first emergency use validation for a COVID-19 vaccine and emphasizes need for equitable global access


Useful Sources for Latest Developments and News

WHO: Coronavirus disease (COVID-19) pandemic (including links to regional offices)

WHO: COVID-19 vaccines

United Nations: COVID-19 Response

Johns Hopkins University & Medicine: Coronavirus Resource Center

Centers for Disease Control and Prevention

European Centre for Disease Prevention and Control

Médecins Sans Frontières: Response and News Articles

BBC: Covid-19 pandemic: Tracking the global coronavirus outbreak

Harvard Medical School: Coronavirus Resource Center

Our World in Data: Coronavirus Pandemic (COVID-19) - Statistics and Research


Educational Resources:


WHO: COVID-19 Course Series

"Real-time training during global emergencies is critical for effective preparedness and response. The COVID-19 channel provides learning resources for health professionals, decision-makers and the public for the outbreak of coronavirus disease (COVID-19)." (WHO 2020)

WHO: Vaccine Series

Johns Hopkins University: Understanding the COVID-19 Pandemic

The BMJ: Returning to physical activity after covid-19 

Salman D, Vishnubala D, Le Feuvre P, Beaney T, Korgaonkar J, Majeed A, McGregor AH. Returning to physical activity after covid-19. BMJ. 2021 Jan 8;372:m4721. doi: 10.1136/bmj.m4721. PMID: 33419740.


MedShr Open: COVID-19 Weekly Article - Telemedicine and the COVID-19 Pandemic

Last week's COVID-19 Open Article aims to provide a concise overview on some of the potential benefits and challenges presented by the increased use of telemedicine during the COVID-19 pandemic.


Research related to COVID-19

Below is a list of links to organisations who are making great efforts to categorise, evaluate and summarise the vast catalogue of COVID-19 research. If you discover any other great resources please feel free to share these in the comments section below.

Global research on coronavirus disease (COVID-19) - WHO Global research database and links to further research catalogues

LitCovid - a curated literature hub for tracking up-to-date scientific information about COVID-19

Public Health Emergency COVID-19 Initiative - PubMed Central

COVID-19 Science Updates - Centers for Disease Control and Prevention

Coronavirus Disease 2019 (COVID-19) Treatment Guidelines - National Institutes for Health

ClinicalTrials.gov - COVID-19 clinical trials

Finding the evidence: Coronavirus – Knowledge & Library Services - Public Health England

Coronavirus (COVID-19) - Cochrane resources and news - Cochrane



Weekly Update by Dr Ryan Broll, MedShr Open Editorial Team, Medical Education Fellow

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