Coronavirus COVID-19 Weekly Update 14th December 2020

Coronavirus COVID-19 Weekly Update 14th December 2020

Weekly update published on MedShr: 14th December 2020
Last updated: 14th December 2020

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Coronavirus COVID-19 Weekly Update 14th December 2020

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

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Global Impact of COVID-19 to Date

WHO official data, reported on 13th Dec 2020

COVID-19 Cumulative Global Cases

WHO official data, reported on 13th Dec 2020

Total UK COVID-19 Cases

As of 14th Dec 09:00 (GMT) - Data for 24 hour period, reported on 13-12-20

UK total daily cases over past month

COVID-19 in the African Region

As of 14th Dec 09:00 (GMT) - Data for 24 hour period, reported on 13-12-20

COVID-19 in the Eastern Mediterranean Region

As of 14th Dec 09:00 (GMT) - Data for 24 hour period, reported on 13-12-20

Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from scientific journals:


Editorials, Research Articles and Commentary:

The Lancet: Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Voysey M, Clemens SAC, Madhi SA, et al. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet. 2020 Dec 8:S0140-6736(20)32661-1. doi: 10.1016/S0140-6736(20)32661-1. Epub ahead of print. PMID: 33306989; PMCID: PMC7723445.

NEJM: Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Polack FP, Thomas SJ, Kitchin N, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020 Dec 10. doi: 10.1056/NEJMoa2034577. Epub ahead of print. PMID: 33301246.

The Lancet HIV: HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform

Bhaskaran K, Rentsch CT, MacKenna B, et al. HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. The Lancet HIV. 2020 Dec 11. doi: 10.1016/S2352-3018(20)30305-2. Epub ahead of print. Linked comment: https://doi.org/10.1016/S2352-3018(20)30332-5 

PLOS One: Prevalence and predictors of death and severe disease in patients hospitalized due to COVID-19: A comprehensive systematic review and meta-analysis of 77 studies and 38,000 patients

Dorjee K, Kim H, Bonomo E, Dolma R. Prevalence and predictors of death and severe disease in patients hospitalized due to COVID-19: A comprehensive systematic review and meta-analysis of 77 studies and 38,000 patients. PLoS One. 2020 Dec 7;15(12):e0243191. doi: 10.1371/journal.pone.0243191. PMID: 33284825.

The Lancet: Fragmented health systems in COVID-19: rectifying the misalignment between global health security and universal health coverage

Lal A, Erondu NA, Heymann DL, Gitahi G, Yates R. Fragmented health systems in COVID-19: rectifying the misalignment between global health security and universal health coverage. Lancet. 2020 Dec 1:S0140-6736(20)32228-5. doi: 10.1016/S0140-6736(20)32228-5. Epub ahead of print. PMID: 33275906.

Transfus Clin Biol: The impact of COVID-19 pandemic on blood supplies and transfusion services in Eastern Mediterranean Region 

Riyami AZA, Abdella YE, Badawi MA, et al. Transfus Clin Biol. 2020 Dec 1:S1246-7820(20)30161-0. doi: 10.1016/j.tracli.2020.11.002. Epub ahead of print. PMID: 33276150; PMCID: PMC7706593.

J Glob Health: Nigeria's public health response to the COVID-19 pandemic: January to May 2020 (viewpoint)

Dan-Nwafor C, Ochu CL, Elimian K, et al. Nigeria's public health response to the COVID-19 pandemic: January to May 2020. J Glob Health. 2020 Dec;10(2):020399. doi: 10.7189/jogh.10.020399. PMID: 33274062; PMCID: PMC7696244.

J Med Internet Res: Middle East and North Africa SARS-CoV-2 Surveillance: A Longitudinal Trend Analysis

Post L, Marogi E, Moss CB, et al. Middle East and North Africa SARS-CoV-2 Surveillance: A Longitudinal Trend Analysis. J Med Internet Res. 2020 Dec 10. doi: 10.2196/25830. Epub ahead of print. PMID: 33302252.


Latest Developments in the News:

WHO Weekly Situational Reports: Epidemiological and Operational


Africa

WHO (AFRO): WHO urges stronger community role in COVID-19 vaccine rollout

BMJ: Rwanda’s secret weapon against covid-19: trust 

WHO (AFRO): Keeping to the universal health coverage path in Kenya

BBC: Coronavirus in Africa tracker

WHO in the African Region: COVID-19


Eastern Mediterranean

WHO (EMRO): WHO Regional Director's statement for virtual press briefing, 8 December

WHO (EMRO): Islamic Advisory Group reiterates commitment to polio eradication amid COVID-19 pandemic

BBC: Coronavirus vaccine: China jab 86% effective, UAE says

WHO: Regional COVID-19 response: success stories

WHO in the Eastern Mediterranean Region: COVID-19


United Kingdom

BMJ: Lateral flow tests cannot rule out SARS-CoV-2 infection 

BBC: Covid: UK isolation period shortened to 10 days

BMJ: Lightening the viral load to lessen covid-19 severity 

EClinicalMedicine (by The Lancet): The challenges of distributing COVID-19 vaccinations

BBC: Lockdown rules: What Covid tier is your area in and what are the restrictions?

UK Government Advice

Coronavirus (COVID-19) in the UK


Global Health

BMJ: Covid-19: Many poor countries will see almost no vaccine next year, aid groups warn

Nature: Oxford COVID-vaccine paper highlights lingering unknowns about results

BMJ: Covid-19: Pfizer vaccine efficacy was 52% after first dose and 95% after second dose, paper shows 

BMJ: Covid-19: FDA panel votes to approve Pfizer BioNTech vaccine 

The Lancet: Facing up to long COVID

UNICEF: COVID-19: UNICEF warns of continued damage to learning and well-being as number of children affected by school closures soars again

BMJ: Using antibiotics wisely for respiratory tract infection in the era of covid-19 (Practice Pointer) 


Useful Sources for Latest Developments and News

WHO: Coronavirus disease (COVID-19) pandemic (including links to regional offices)

WHO: COVID-19 vaccines

United Nations: COVID-19 Response

Johns Hopkins University & Medicine: Coronavirus Resource Center

Centers for Disease Control and Prevention

European Centre for Disease Prevention and Control

Médecins Sans Frontières: Response and News Articles

BBC: Covid-19 pandemic: Tracking the global coronavirus outbreak

Financial Times: Coronavirus tracker: the latest figures as countries fight Covid-19 resurgence

Harvard Medical School: Coronavirus Resource Center

Our World in Data: Coronavirus Pandemic (COVID-19) - Statistics and Research


Educational Resources:


WHO: COVID-19 Course Series

"Real-time training during global emergencies is critical for effective preparedness and response. The COVID-19 channel provides learning resources for health professionals, decision-makers and the public for the outbreak of coronavirus disease (COVID-19)." (WHO 2020)

WHO: Vaccine Series

  1. How do vaccines work?

  2. How are vaccines developed?

  3. Manufacturing, safety and quality control of vaccines

  4. Tips for professional reporting on COVID-19 vaccines


MedShr Open: COVID-19 Weekly Article - Malaria and COVID-19

Last week's COVID-19 Open Article considers the challenge of managing COVID-19 in malaria endemic settings, and focuses on strategies for maintaining essential services for malaria during this time.


Public Health Emergency COVID-19 Initiative - PubMed Central

An open collection of COVID-19 and coronavirus-related publications, and the available data supporting them, from over 50 publishers to support the ongoing public health emergency response efforts (PMC).

Other Useful Resources:

Intensive Care Society (UK) Covid-19 Resource Hub

The Mid Yorkshire Hospitals NHS Trust COVID-19 Bulletins - A weekly bulletin detailing the "latest guidelines, research and reports relating to COVID-19"

NHS England: Coronavirus guidance for clinicians and NHS managers

CDC: COVID-19 Science Updates



Weekly Update by Dr Ryan Broll, MedShr Open Editorial Team, Medical Education Fellow

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