Coronavirus COVID-19 Weekly Update 16th November 2020

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Weekly update published on MedShr: 16th November 2020
Last updated: 16th November 2020

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Coronavirus COVID-19 Weekly Update 16th November 2020

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of doctors to help improve patient care. Include #COVID19 in your case title.

Please email COVID@medshr.net if you have any data, publications or information you would like to share.


Global Impact of COVID-19 to Date

WHO official data, reported on 15th Nov 2020

COVID-19 Cumulative Global Cases

WHO official data, reported on 15th Nov 2020

Total UK COVID-19 Cases

As of 16th Nov 09:00 (GMT) - Data for 24 hour period, reported on 15-11-20

Total UK daily cases over past month

COVID-19 in the African Region

As of 16th Nov 09:00 (GMT) - Data for 24 hour period, reported on 15-11-20

COVID-19 in the Eastern Mediterranean Region

As of 16th Nov 09:00 (GMT) - Data for 24 hour period, reported on 15-11-20

Latest Developments in the News:

WHO Weekly Situational Reports: Epidemiological and Operational


Africa

WHO: Nearly 1 in 5 COVID-19 deaths in the African region linked to diabetes 

The Lancet Respiratory Medicine: COVID-19 vaccine trials in Africa

The Lancet: Action needed now to prevent further increases in measles and measles deaths in the coming years  

The Lancet Global Health: What could fair allocation of an efficacious COVID-19 vaccine look like in South Africa?

BBC: Coronavirus in Africa tracker

WHO in the African Region: COVID-19


Eastern Mediterranean

MSF: COVID-19 in northwest Syria: Taking risks simply to survive 

BBC: Coronavirus: Lebanon to impose new lockdown despite economic cost

WHO: Regional COVID-19 response: success stories

WHO in the Eastern Mediterranean Region: COVID-19


United Kingdom

BMJ: Covid-19: Hospitals forced to suspend routine care amid second surge 

BMJ: Covid-19: NHS staff express scepticism over promised twice weekly testing 

NEJM: Trying to “Protect the NHS” in the United Kingdom  (perspective)

The Lancet: More support needed for UK charity-funded medical research (comment) 

The Guardian: Damage to multiple organs recorded in 'long Covid' cases 

BBC: Covid vaccine: Major new trial starts in UK 

BBC: Covid-19 in the UK: How many coronavirus cases are there in your area? 

UK Government Advice

Coronavirus (COVID-19) in the UK


Global Health

Nature: COVID vaccination logistics: five steps to take now 

Nature: What Pfizer's landmark COVID vaccine results mean for the pandemic 

Nature: COVID vaccination logistics: five steps to take now 

BMJ: Covid-19 vaccines: Should we allow human challenge studies to infect healthy volunteers with SARS-CoV-2?

BMJ: Covid-19: FDA authorises neutralising antibody bamlanivimab for non-admitted patients  

BMJ: Trends in suicide during the covid-19 pandemic

BMJ: Covid-19: Denmark to kill 17 million minks over mutation that could undermine vaccine effort  

MSF: Governments must demand all coronavirus COVID-19 vaccine deals are made public 

The Lancet: Leveraging the COVID-19 response to end preventable child deaths from pneumonia


Useful Sources for Latest Developments and News

WHO: Coronavirus disease (COVID-19) pandemic (including links to regional offices)

United Nations: COVID-19 Response

Johns Hopkins University & Medicine: Coronavirus Resource Center

Centers for Disease Control and Prevention

European Centre for Disease Prevention and Control

Médecins Sans Frontières: Response and News Articles

BBC: Covid-19 pandemic: Tracking the global coronavirus outbreak

Financial Times: Coronavirus tracker: the latest figures as countries fight Covid-19 resurgence

Harvard Medical School: Coronavirus Resource Center

Our World in Data: Coronavirus Pandemic (COVID-19) - Statistics and Research


Educational Resources:


WHO: COVID-19 Course Series

"Real-time training during global emergencies is critical for effective preparedness and response. The COVID-19 channel provides learning resources for health professionals, decision-makers and the public for the outbreak of coronavirus disease (COVID-19)." (WHO 2020)


MedShr Open: COVID-19 Weekly Article - Vaccine Development Challenges

Last week's COVID-19 Open Article follows our previous article on the progress in the search for a vaccine against SARS-CoV-2 (COVID-19), and focuses on the challenges that must be overcome in developing and distributing a new vaccine. The article also discusses factors specific to different patient groups which are relevant for selecting a safe and effective vaccine.

Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from scientific journals:


Editorials, Research Articles and Commentary:

BMC Infectious Diseases: Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence

Tamuzi JL, Ayele BT, Shumba CS, et al. Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence. BMC Infect Dis. 2020 Oct 9;20(1):744. doi: 10.1186/s12879-020-05450-4. PMID: 33036570; PMCID: PMC7545798.

The Lancet: Cost-effectiveness of public health strategies for COVID-19 epidemic control in South Africa: a microsimulation modelling study

Reddy KP, Shebl FM, Foote JHA, et al. Cost-effectiveness of public health strategies for COVID-19 epidemic control in South Africa: a microsimulation modelling study. Lancet Glob Health. 2020 Nov 11:S2214-109X(20)30452-6. doi: 10.1016/S2214-109X(20)30452-6. Epub ahead of print. PMID: 33188729.

BMJ: Accuracy of UK Rapid Test Consortium (UK-RTC) "AbC-19 Rapid Test" for detection of previous SARS-CoV-2 infection in key workers: test accuracy study

Mulchandani R, Jones HE, Taylor-Phillips S, et al. Accuracy of UK Rapid Test Consortium (UK-RTC) "AbC-19 Rapid Test" for detection of previous SARS-CoV-2 infection in key workers: test accuracy study. BMJ. 2020 Nov 11;371:m4262. doi: 10.1136/bmj.m4262. PMID: 33177070; PMCID: PMC7656121.

NEJM: SARS-CoV-2 Transmission among Marine Recruits during Quarantine

Letizia AG, Ramos I, Obla A, et al. SARS-CoV-2 Transmission among Marine Recruits during Quarantine. N Engl J Med. 2020 Nov 11. doi: 10.1056/NEJMoa2029717. Epub ahead of print. PMID: 33176093.

EClinicalMedicine (by The Lancet): Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis

Sze S, Pan D, Nevill CR, et al. Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis. ClinicalMedicine, Volume 0, Issue 0, 100630. 2020 Nov 12. DOI: 10.1016/j.eclinm.2020.100630

Science: Robust neutralizing antibodies to SARS-CoV-2 infection persist for months

Wajnberg A, Amanat F, Firpo A, et al. Robust neutralizing antibodies to SARS-CoV-2 infection persist for months. Science. 2020 Oct 28:eabd7728. doi: 10.1126/science.abd7728. Epub ahead of print. PMID: 33115920.

Contemporary Clinical Trials: Covid-19 pandemic research opportunity: Is the Middle East & North Africa (MENA) missing out?

Ibrahim H, Kamour AM, Harhara T, Gaba WH, Nair SC. Covid-19 pandemic research opportunity: Is the Middle East & North Africa (MENA) missing out? Contemp Clin Trials. 2020 Sep;96:106106. doi: 10.1016/j.cct.2020.106106. Epub 2020 Aug 8. PMID: 32781230.


Public Health Emergency COVID-19 Initiative - PubMed Central

An open collection of COVID-19 and coronavirus-related publications, and the available data supporting them, from over 50 publishers to support the ongoing public health emergency response efforts (PMC).

Other Useful Resources:

Intensive Care Society (UK) Covid-19 Resource Hub

The Mid Yorkshire Hospitals NHS Trust COVID-19 Bulletins - A weekly bulletin detailing the "latest guidelines, research and reports relating to COVID-19"

NHS England: Coronavirus guidance for clinicians and NHS managers

CDC: COVID-19 Science Updates


Weekly Update by Dr Ryan Broll, MedShr Open Editorial Team, Medical Education Fellow

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