Coronavirus COVID-19 Weekly Update 21st September 2020

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Weekly update published on MedShr: 21st September 2020
Last updated: 21st September 2020

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Coronavirus COVID-19 Weekly Update 21st September 2020

This update will be published weekly at 12pm GMT on Mondays and aims to provide clinicians and the public with an overview of the latest data, guidelines, key publications and policy around COVID-19, with links to essential resources and information.

If you are a healthcare professional, please join the discussion on these latest COVID-19 cases on MedShr:

Please post any COVID-19 cases, images or learning points from your clinical practice on MedShr - share key knowledge and experience with a global network of doctors to help improve patient care. Include #COVID19 in your case title.


Please email COVID@medshr.net if you have any data, publications or information you would like to share.

Global Impact of COVID-19 to Date

WHO official data, reported on 20th Sept 20

COVID-19 Cumulative Global Cases

WHO official data, reported on 20th Sept 20

Total UK COVID-19 Cases

As of 21st Sept 09:00 (GMT) - Data for 24 hour period on 20-09-20

Total UK daily cases over past month

COVID-19 in the African Region

As of 21st Sept 09:00 (GMT) - Data for 24 hour period on 20-09-20

COVID-19 in the Eastern Mediterranean Region

As of 21st Sept 09:00 (GMT) - Data for 24 hour period on 20-09-20

Latest Developments:

WHO Weekly Situational Reports: Epidemiological and Operational


Africa

WHO: WHO encouraged by South Africa’s declining COVID-19 trend

WHO: World patient Safety Day –COVID-19 pandemic amplifies importance of health workers’ safety

WHO: Expert panel endorses protocol for COVID-19 herbal medicine clinical trials

WHO: Children’s continued learning and welfare should be at the centre of decisions around school re-open

BBC: Covid-19 in Africa: Fighting fake news about coronavirus

MSF: Central African Republic - In times of COVID-19, malaria remains the number one killer of children in CAR

WHO in the African Region: COVID-19


Eastern Mediterranean

WHO: Statement by WHO's Regional Director on a resurgence of COVID-19 cases in the Region

WHO: Health worker safety: a priority for patient safety

WHO: Republic of Korea and WHO Afghanistan sign arrangement to support the COVID-19 response

WHO: WHO makes SARS-CoV-2 antibody ELISA tests available in Islamic Republic of Iran with support from Robert Koch Institute

WHO in the Eastern Mediterranean Region: COVID-19


United Kingdom

GOV.UK: Largest testing programme for coronavirus reinforces need for vigilance

BBC: Covid: UK at 'critical point' in pandemic, top scientists to warn

BBC: Covid: Can a 'circuit break' halt the second wave?

BBC: Coronavirus testing: What's going wrong?

The Guardian: BAME Britons still lack protection from Covid, says doctors' chief

UK Government Advice

Coronavirus (COVID-19) in the UK


Global Health

WHO Europe: Statement – Covid-19: Regional coherence and a spirit of collective support is crucial

WHO: Coronavirus disease (COVID-19) pandemic

United Nations: COVID-19 Response

Johns Hopkins University & Medicine: Coronavirus Resource Center

Centers for Disease Control and Prevention

European Centre for Disease Prevention and Control

Médecins Sans Frontières


Join the World Health Organization's #WearAMask Challenge

Educational Resources:


WHO: COVID-19 Course Series

"Real-time training during global emergencies is critical for effective preparedness and response. The COVID-19 channel provides learning resources for health professionals, decision-makers and the public for the outbreak of coronavirus disease (COVID-19)." (WHO 2020)


Latest COVID-19 Publications and Guidelines:

A selection of recent publications and useful clinical guidance from high impact journals:


Practice Points from the BMJ:

BMJ: Testing for SARS-CoV-2 antibodies

Watson Jessica, Richter Alex, Deeks Jonathan. Testing for SARS-CoV-2 antibodies BMJ 2020; 370 :m3325

BMJ: A living WHO guideline on drugs for covid-19

Lamontagne François, Agoritsas Thomas, Macdonald Helen, Leo Yee-Sin, Diaz Janet, Agarwal Arnav et al. A living WHO guideline on drugs for covid-19 BMJ 2020; 370 :m3379


Research Articles and Commentary:

PLoS Medicine: Adverse outcomes and mortality in users of non-steroidal anti-inflammatory drugs who tested positive for SARS-CoV-2: A Danish nationwide cohort study

Lund LC, Kristensen KB, Reilev M, Christensen S, Thomsen RW, et al. (2020) Adverse outcomes and mortality in users of non-steroidal anti-inflammatory drugs who tested positive for SARS-CoV-2: A Danish nationwide cohort study. PLOS Medicine 17(9): e1003308. https://doi.org/10.1371/journal.pmed.1003308

NEJM: Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States — The NIH RADx Initiative

Tromberg BJ, Schwetz TA, Pérez-Stable EJ, et al. Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States - The NIH RADx Initiative. N Engl J Med. 2020;383(11):1071-1077. doi:10.1056/NEJMsr2022263

JAMA: Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19 - The CoDEX Randomized Clinical Trial

Tomazini BM, Maia IS, Cavalcanti AB, et al. Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial. JAMA. Published online September 02, 2020. doi:10.1001/jama.2020.17021

The Lancet: Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial

Furtado RHM, Berwanger O, Fonseca HA, et al. Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial [published online ahead of print, 2020 Sep 4]. Lancet. 2020;S0140-6736(20)31862-6. doi:10.1016/S0140-6736(20)31862-6


Public Health Emergency COVID-19 Initiative - PubMed Central

An open collection of COVID-19 and coronavirus-related publications, and the available data supporting them, from over 50 publishers to support the ongoing public health emergency response efforts (PMC).

Other Useful Resources:

Intensive Care Society (UK) Covid-19 Resource Hub

The Mid Yorkshire Hospitals NHS Trust COVID-19 Bulletins - A weekly bulletin detailing the "latest guidelines, research and reports relating to COVID-19"

NHS England: Coronavirus guidance for clinicians and NHS managers

CDC: COVID-19 Science Updates


Weekly Update by Dr Ryan Broll, MedShr Open Editorial Team, Medical Education Fellow

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